steele, although Aleexi's post is technically correct, In don't think it address what you're asking exactly. It depends on how far you're boring a particular block.
Like Alexi posted, if you bore a block too far, but it is intact, you may have bored it to the point that the bores will not remain round under operation. The more power you make, the thicker the bore needs to be to remain stable. A heavily NOS or blown MK IV with a .060 bore can fail. The walls go barrel shape with every firing, and evendually fail, plus you're probably losing power up to the point that it fails. They usually fail on the major thrust side of the cylinder. Either the out side, or valley side of the cylinder depending if its a odd or even numbered cylinder.
With regards to the difference between production MK IVs and Bowties, or aftermarket, it because of the way the block is cast. If you bored a production MK IV to 4.56 or 4.60, you would have to worry about failure during operation. It wouldn't have a cylinder left to fail. It would be GONE, nothing but water jacket. The cylinder walls of a MK IV just aren't that thick.
The Bowties, and others have what is called siamesed cylinders. The walls are cast so thick that there is no room left between cylinders for water to circulate. All 4 cylinders are cast as a single block from one end to the other, with no space between cylinders. To give you an idea how thick the castings are, a production MK IV bored .060 has a thinner cylinder wall than a late Bowtie bored 4.625